Dermal-Tissue Fillers

With aging, a decrease in the subcutaneous fat tissue on our face and downward displacement with the effect of gravity is observed. While the reduction of subcutaneous fat tissue causes the muscles that perform facial expressions to become superficial and to become evident on the skin with facial expressions, that is, the formation of wrinkles, it causes discharge in the upper face with the downward movement of the fat tissue. With fillers, it is possible to replace the loss of volume in this aging process and reduce the visibility of fine wrinkles. 

With fillers; thickening of thin lips, softening of folds and wrinkles on the face, improving the appearance of sunken scars, clarifying facial contours, smoothing the transition between the cheeks and under the eyes can be done. Thus, while the early signs of aging are eliminated, the time for surgery is extended. However, in patients who will require surgical procedures such as facelift or eyebrow lifting, the desired result cannot be obtained with fillers.

There are many dermal fillers available today. The most commonly used one is hyaluronic acid, and it is often used for lip thickening, opening fine wrinkles, and softening the under-eye cheek transition. In addition, it is used to plump the cheek area, thus creating a relative lifting effect on the middle face and softening the transition between the cheek and nose, which is called nasolabial. Hyaluronic acid is a compound that normally exists in our skin and has the ability to absorb water quickly. For this reason, as soon as it is made, it gives volume to the skin and moisturizes it while softening it. Hyaluronic acid fillers are temporary fillers and dissolve in an average of 6-12 months.

Calcium hydroxyapatite (radiesse) is another filling material and consists of 30% calcium hydroxyapatite and 70% carrier gel. Its effect lasts for at least 1 year, and it stimulates new collagen formation, which increases the volume of the skin over time. It is especially done on bone protrusions such as highlighting the cheekbones and lower jaw contour on the cheek, eliminating the collapse in the temple area or correcting the ridge of the nose . There is no need for a skin test before the application.

Poly-L-Lactic acid (Sculptra) , on the other hand, stimulates synthetic, biocompatible and immune system ineffective fibroblasts, providing more collagen production and thus has a filling structure that provides volume increase. It is especially suitable for use in AIDS-related facial volume losses. Unlike other fillings, its effect appears after at least 4 weeks and 2-3 sessions should be performed with 4-6 week intervals. There is no need for a skin test before the application.

Autologous cell therapy (Azficel-T) is used for mild and severe stiffness of the nasolabial fold between the cheek and nose. It is a personalized treatment. Fibroblasts are separated and multiplied in the laboratory environment from the skin sample taken from behind the ear and injected into the person in 3 sessions with an interval of 3-6 weeks. Although it is known to last for at least 6 months, it may take longer.